Other iPSC-derived Cells

Although human iPS cells have many advantages over existing models, one drawback is that differentiation into the desired cell type is a time and labor intensive process. Our proprietary technology allows for rapid, reproducible differentiation of human iPSC-derived GABAergic neurons without sacrificing purity.

iPSC-derived GABAergic Neurons from Healthy and Affected Donors

Elixirgen Scientific’s human iPSC-derived GABAergic neurons are created using human iPS cells made available through a license from The California Institute for Regenerative Medicine (CIRM).

All of our iPSC-derived GABAergic neurons are differentiated using our proprietary technology that utilizes a potent cocktail of key transcription factors to transform iPSCs into high-quality, differentiated GABAergic neurons. The CIRM iPS cell repository includes over 1,500 iPS cell lines, so please contact us if you would like GABAergic neurons derived from a specific donor cell line.

Advantages

  • Fast differentiation and maturation
  • Highly pure population
  • No genetic footprint
  • Multiple donors and disease types to choose from
Cat No. Donor Information Disease Status
GA-CW50065 Human iPSC-Derived GABAergic Neurons (F, 74 yr) Healthy
GA-CW10149 Human iPSC-Derived GABAergic Neurons (M, 38 yr) Healthy
GA-CW20300 Human iPSC-Derived GABAergic Neurons (M, 10 yr) Healthy

You might also be interested in....

Quick-Neuron™ GABAergic Differentiation Kits & Media

Our Quick-Neuron™ GABAergic differentiation kits allow researchers to quickly, easily, and efficiently differentiate their iPS cell line into GABAergic neurons. The kits are available in Sendai virus and synthetic mRNA formats, which give comparable efficiencies and do not leave a genetic footprint.

Cat No. Product Name Description
GA-SeV SeV Complete Kit This kit differentiates human pluripotent stem cells into GABAergic neurons in 10 days using Sendai Virus.
GA-CW10149 mRNA Complete Kit This kit differentiates human pluripotent stem cells into GABAergic neurons in 10 days using synthetic mRNA.
GA-MM Maintenance Medium This medium maintains differentiated GABAergic neurons.

Characterization

Immunofluorescent staining on day 10 that demonstrates typical neurite outgrowth and homogenous expression of the pan-neuronal marker TUBB3 and GABAergic neuron-specific marker PVALB.

MEA data (TBD)
Expression profile (TBD)

Frequently Asked Questions

Do you have any videos to show the protocol?

Yes. You can watch our step-by-step protocol videos on our website here.

Is there any difference in the differentiation efficiency between an mRNA-based and a SeV-based kit?

Based on our data, for example, the percentages of TUBB3+neurons differentiated using Quick-Neuron™ Cholinergic mRNA and SeV were 93% and 88%, respectively. Thus, there is not much differences in the differentiation efficiency between an mRNA-based and a SeV-based kit.

Is there any difference in the differentiation efficiency between an mRNA-based and a SeV-based kit?

Based on our data, for example, the percentages of TUBB3+neurons differentiated using Quick-Neuron™ Cholinergic mRNA and SeV were 93% and 88%, respectively. Thus, there is not much differences in the differentiation efficiency between an mRNA-based and a SeV-based kit.